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Selection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy

Molecular radiotherapy combines the advantages of systemic administration of highly specific antibodies or peptides and the localized potency of ionizing radiation. A potential target for molecular radiotherapy is the cell surface antigen CD44v6, which is overexpressed in numerous cancers, with limi...

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Detalles Bibliográficos
Autores principales: Mortensen, A. C. L., Berglund, H., Segerström, L., Walle, M., Hofström, C., Persson, H., Nygren, P.-Å., Nilvebrant, J., Frejd, F. Y., Nestor, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673843/
https://www.ncbi.nlm.nih.gov/pubmed/38001360
http://dx.doi.org/10.1038/s41598-023-47891-2