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Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status

Bone formation is a highly energy-demanding process that can be impacted by metabolic disorders. Glucose has been considered the principal substrate for osteoblasts, although fatty acids are also important for osteoblast function. Here, we report that osteoblasts can derive energy from endogenous fa...

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Detalles Bibliográficos
Autores principales: Nandy, Ananya, Helderman, Ron C. M., Thapa, Santosh, Jayapalan, Shobana, Richards, Alison, Narayani, Nikita, Czech, Michael P., Rosen, Clifford J., Rendina-Ruedy, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673934/
https://www.ncbi.nlm.nih.gov/pubmed/38001111
http://dx.doi.org/10.1038/s41413-023-00297-2