Cargando…
Lipolysis supports bone formation by providing osteoblasts with endogenous fatty acid substrates to maintain bioenergetic status
Bone formation is a highly energy-demanding process that can be impacted by metabolic disorders. Glucose has been considered the principal substrate for osteoblasts, although fatty acids are also important for osteoblast function. Here, we report that osteoblasts can derive energy from endogenous fa...
Autores principales: | Nandy, Ananya, Helderman, Ron C. M., Thapa, Santosh, Jayapalan, Shobana, Richards, Alison, Narayani, Nikita, Czech, Michael P., Rosen, Clifford J., Rendina-Ruedy, Elizabeth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673934/ https://www.ncbi.nlm.nih.gov/pubmed/38001111 http://dx.doi.org/10.1038/s41413-023-00297-2 |
Ejemplares similares
-
Untargeted metabolomics in primary murine bone marrow stromal cells reveals distinct profile throughout osteoblast differentiation
por: Misra, Biswapriya B., et al.
Publicado: (2021) -
Endocrinal metabolic regulation on the skeletal system in post-menopausal women
por: Thapa, Santosh, et al.
Publicado: (2022) -
Effects of PTH on osteoblast bioenergetics in response to glucose
por: DeMambro, Victoria E., et al.
Publicado: (2023) -
Influence of Cholesterol on the Regulation of Osteoblast Function
por: Akhmetshina, Alena, et al.
Publicado: (2023) -
Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks
por: Rendina-Ruedy, Elizabeth, et al.
Publicado: (2022)