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Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers

The heterogenous treatment response of tumor cells limits the effectiveness of cancer therapy. While this heterogeneity has been linked to cell-to-cell variability within the complex tumor microenvironment, a quantitative biomarker that identifies and characterizes treatment-resistant cell populatio...

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Detalles Bibliográficos
Autores principales: Pekeč, Tina, Venkatachalapathy, Saradha, Shim, Anne R., Paysan, Daniel, Grzmil, Michal, Schibli, Roger, Béhé, Martin, Shivashankar, G. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673941/
https://www.ncbi.nlm.nih.gov/pubmed/38001169
http://dx.doi.org/10.1038/s41598-023-47287-2