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Impact of formalin fixation on mismatch repair protein evaluation by immunohistochemistry

Mismatch repair/microsatellite instability (MMR/MSI) status in colorectal cancer (CRC) has become fundamental as a diagnostic, prognostic, and predictive factor. MMR immunohistochemistry (IHC) is considered a simple and reliable approach; however, its effectiveness depends on pre-analytic factors. A...

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Detalles Bibliográficos
Autores principales: Grillo, Federica, Ali, Murad, Paudice, Michele, Pigozzi, Simona, Anselmi, Giorgia, Scabini, Stefano, Sciallero, Stefania, Piol, Nataniele, Mastracci, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673985/
https://www.ncbi.nlm.nih.gov/pubmed/37773452
http://dx.doi.org/10.1007/s00428-023-03661-z