Discovery of a novel cardiac-specific myosin modulator using artificial intelligence-based virtual screening

Direct modulation of cardiac myosin function has emerged as a therapeutic target for both heart disease and heart failure. However, the development of myosin-based therapeutics has been hampered by the lack of targeted in vitro screening assays. In this study we use Artificial Intelligence-based vir...

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Detalles Bibliográficos
Autores principales: Parijat, Priyanka, Attili, Seetharamaiah, Hoare, Zoe, Shattock, Michael, Kenyon, Victor, Kampourakis, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673995/
https://www.ncbi.nlm.nih.gov/pubmed/38001148
http://dx.doi.org/10.1038/s41467-023-43538-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673995/
https://www.ncbi.nlm.nih.gov/pubmed/38001148
http://dx.doi.org/10.1038/s41467-023-43538-y

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