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Discovery of a novel cardiac-specific myosin modulator using artificial intelligence-based virtual screening
Direct modulation of cardiac myosin function has emerged as a therapeutic target for both heart disease and heart failure. However, the development of myosin-based therapeutics has been hampered by the lack of targeted in vitro screening assays. In this study we use Artificial Intelligence-based vir...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10673995/ https://www.ncbi.nlm.nih.gov/pubmed/38001148 http://dx.doi.org/10.1038/s41467-023-43538-y |