PBPK Modeling of Azithromycin Systemic Exposure in a Roux-en-Y Gastric Bypass Surgery Patient Population

In this investigation, PBPK modeling using the Simcyp(®) Simulator was performed to evaluate whether Roux-en-Y gastric bypass (RYGB) surgery impacts the oral absorption and bioavailability of azithromycin. An RYGB surgery patient population was adapted from the published literature and verified usin...

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Detalles Bibliográficos
Autores principales: Avvari, Suvarchala Kiranmai, Cusumano, Jaclyn A., Jogiraju, Vamshi Krishna, Manchandani, Pooja, Taft, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674169/
https://www.ncbi.nlm.nih.gov/pubmed/38004500
http://dx.doi.org/10.3390/pharmaceutics15112520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674169/
https://www.ncbi.nlm.nih.gov/pubmed/38004500
http://dx.doi.org/10.3390/pharmaceutics15112520

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