PBPK Modeling of Azithromycin Systemic Exposure in a Roux-en-Y Gastric Bypass Surgery Patient Population

In this investigation, PBPK modeling using the Simcyp(®) Simulator was performed to evaluate whether Roux-en-Y gastric bypass (RYGB) surgery impacts the oral absorption and bioavailability of azithromycin. An RYGB surgery patient population was adapted from the published literature and verified usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Avvari, Suvarchala Kiranmai, Cusumano, Jaclyn A., Jogiraju, Vamshi Krishna, Manchandani, Pooja, Taft, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674169/
https://www.ncbi.nlm.nih.gov/pubmed/38004500
http://dx.doi.org/10.3390/pharmaceutics15112520

Ejemplares similares

Ejemplares similares