Challenges Related to Acquisition of Physiological Data for Physiologically Based Pharmacokinetic (PBPK) Models in Postpartum, Lactating Women and Breastfed Infants—A Contribution from the ConcePTION Project

Physiologically based pharmacokinetic (PBPK) modelling is a bottom-up approach to predict pharmacokinetics in specific populations based on population-specific and medicine-specific data. Using an illustrative approach, this review aims to highlight the challenges of incorporating physiological data...

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Detalles Bibliográficos
Autores principales: Van Neste, Martje, Bogaerts, Annick, Nauwelaerts, Nina, Macente, Julia, Smits, Anne, Annaert, Pieter, Allegaert, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674226/
https://www.ncbi.nlm.nih.gov/pubmed/38004596
http://dx.doi.org/10.3390/pharmaceutics15112618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674226/
https://www.ncbi.nlm.nih.gov/pubmed/38004596
http://dx.doi.org/10.3390/pharmaceutics15112618

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