Safety and Toxicology Study of Hu7691, a Novel AKT Inhibitor, following Oral Administration in Rats

Hu7691 represents a novel Pan-Akt kinase inhibitor, demonstrating excellent selectivity towards non-AGC kinase families and pronounced inhibitory effects on the proliferation of multiple tumor cell lines. However, there is currently a notable absence of in vivo toxicological research evidence concer...

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Detalles Bibliográficos
Autores principales: Gai, Renhua, Chen, Chao, Zhang, Wei, Ma, Jian, Wang, Xiaomeng, Chi, Xiaoqing, Li, Guangxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674281/
https://www.ncbi.nlm.nih.gov/pubmed/37999532
http://dx.doi.org/10.3390/toxics11110880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674281/
https://www.ncbi.nlm.nih.gov/pubmed/37999532
http://dx.doi.org/10.3390/toxics11110880

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