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Safety and Toxicology Study of Hu7691, a Novel AKT Inhibitor, following Oral Administration in Rats
Hu7691 represents a novel Pan-Akt kinase inhibitor, demonstrating excellent selectivity towards non-AGC kinase families and pronounced inhibitory effects on the proliferation of multiple tumor cell lines. However, there is currently a notable absence of in vivo toxicological research evidence concer...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674281/ https://www.ncbi.nlm.nih.gov/pubmed/37999532 http://dx.doi.org/10.3390/toxics11110880 |