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Virus-like Particle Vaccines of Infectious Bursal Disease Virus Expressed in Escherichia coli Are Highly Immunogenic and Protect against Virulent Strain

Objectives: Infectious bursal disease virus (IBDV) is a highly contagious, acutely infectious agent that causes immunosuppression in chickens. We expressed IBDV VP2 proteins in Escherichia coli (E. coli) to develop an effective virus-like-particles (VLPs) vaccine and evaluated its immunogenicity. Me...

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Detalles Bibliográficos
Autores principales: Ji, Pengchao, Li, Tiantian, Wu, Yanan, Zhao, Qi, Li, Lu, Shi, Xuejian, Jiang, Wenting, Wang, Jiabin, Wang, Panpan, Wang, Tingting, Jiang, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674347/
https://www.ncbi.nlm.nih.gov/pubmed/38005855
http://dx.doi.org/10.3390/v15112178