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HIV-1 Remission: Accelerating the Path to Permanent HIV-1 Silencing

Despite remarkable progress, a cure for HIV-1 infection remains elusive. Rebound competent latent and transcriptionally active reservoir cells persevere despite antiretroviral therapy and rekindle infection due to inefficient proviral silencing. We propose a novel “block-lock-stop” approach, entaili...

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Detalles Bibliográficos
Autores principales: Lyons, Danielle E., Kumar, Priti, Roan, Nadia R., Defechereux, Patricia A., Feschotte, Cedric, Lange, Ulrike C., Murthy, Niren, Sameshima, Pauline, Verdin, Eric, Ake, Julie A., Parsons, Matthew S., Nath, Avindra, Gianella, Sara, Smith, Davey M., Kallas, Esper G., Villa, Thomas J., Strange, Richard, Mwesigwa, Betty, Furler O’Brien, Robert L., Nixon, Douglas F., Ndhlovu, Lishomwa C., Valente, Susana T., Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674359/
https://www.ncbi.nlm.nih.gov/pubmed/38005849
http://dx.doi.org/10.3390/v15112171