Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions

The design, synthesis, and evaluation of novel non-steroidal anti-inflammatory drugs (NSAIDs) with better activity and lower side effects are big challenges today. In this work, two 5-acetamido-2-hydroxy benzoic acid derivatives were proposed, increasing the alkyl position (methyl) in an acetamide m...

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Detalles Bibliográficos
Autores principales: Santos, Cleydson B. R., Lobato, Cleison C., Ota, Sirlene S. B., Silva, Rai C., Bittencourt, Renata C. V. S., Freitas, Jofre J. S., Ferreira, Elenilze F. B., Ferreira, Marília B., Silva, Renata C., De Lima, Anderson B., Campos, Joaquín M., Borges, Rosivaldo S., Bittencourt, José A. H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674373/
https://www.ncbi.nlm.nih.gov/pubmed/38004449
http://dx.doi.org/10.3390/ph16111584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674373/
https://www.ncbi.nlm.nih.gov/pubmed/38004449
http://dx.doi.org/10.3390/ph16111584

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