Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

The high expression of the ATP-binding cassette (ABC) drug transporter ABCG2 in cancer cells contributes to the emergence of multidrug resistance (MDR) in individuals afflicted with either solid tumors or blood cancers. MDR poses a major impediment in the realm of clinical cancer chemotherapy. Recen...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Pu, Murakami, Megumi, Li, Yen-Ching, Huang, Yang-Hui, Chang, Yu-Tzu, Hung, Tai-Ho, Wu, Yu-Shan, Ambudkar, Suresh V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674403/
https://www.ncbi.nlm.nih.gov/pubmed/38004460
http://dx.doi.org/10.3390/ph16111595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674403/
https://www.ncbi.nlm.nih.gov/pubmed/38004460
http://dx.doi.org/10.3390/ph16111595

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