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Ethylmethylhydroxypyridine Succinate Is an Inhibitor but Not a Substrate of ABCB1 and SLCO1B1

2-Ethyl-6-methyl-3-hydroxypyridine succinate (EMHPS, Mexidol) is an original antioxidant and an anti-ischemic drug with the possibility of wide applications in the complex therapy of diseases, accompanied by the development of oxidative stress and ischemia; for example, ischemic stroke, chronic cere...

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Detalles Bibliográficos
Autores principales: Shchulkin, Aleksey V., Erokhina, Pelageya D., Goncharenko, Anna V., Mylnikov, Pavel Yu., Chernykh, Ivan V., Abalenikhina, Yulia V., Kotliarova, Maria S., Yakusheva, Elena N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674565/
https://www.ncbi.nlm.nih.gov/pubmed/38004395
http://dx.doi.org/10.3390/ph16111529