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Compromised NHE8 Expression Is Responsible for Vitamin D-Deficiency Induced Intestinal Barrier Dysfunction

Objectives: Vitamin D (VitD) and Vitamin D receptor (VDR) are suggested to play protective roles in the intestinal barrier in ulcerative colitis (UC). However, the underlying mechanisms remain elusive. Evidence demonstrates that Na(+)/H(+) exchanger isoform 8 (NHE8, SLC9A8) is essential in maintaini...

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Detalles Bibliográficos
Autores principales: Guo, Yaoyu, Li, Yanni, Tang, Zeya, Geng, Chong, Xie, Xiaoxi, Song, Shuailing, Wang, Chunhui, Li, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674576/
https://www.ncbi.nlm.nih.gov/pubmed/38004229
http://dx.doi.org/10.3390/nu15224834