Human Pancreatic Islets React to Glucolipotoxicity by Secreting Pyruvate and Citrate

Progressive decline in pancreatic beta-cell function is central to the pathogenesis of type 2 diabetes (T2D). Here, we explore the relationship between the beta cell and its nutritional environment, asking how an excess of energy substrate leads to altered energy production and subsequent insulin se...

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Detalles Bibliográficos
Autores principales: Perrier, Johan, Nawrot, Margaux, Madec, Anne-Marie, Chikh, Karim, Chauvin, Marie-Agnès, Damblon, Christian, Sabatier, Julia, Thivolet, Charles H., Rieusset, Jennifer, Rautureau, Gilles J. P., Panthu, Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674605/
https://www.ncbi.nlm.nih.gov/pubmed/38004183
http://dx.doi.org/10.3390/nu15224791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674605/
https://www.ncbi.nlm.nih.gov/pubmed/38004183
http://dx.doi.org/10.3390/nu15224791

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