Cargando…

A Single-Run HPLC–MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis

The treatment of drug-resistant Mycobacterium tuberculosis relies on complex antibiotic therapy. Inadequate antibiotic exposure can lead to treatment failure, acquired drug resistance, and an increased risk of adverse events. Therapeutic drug monitoring (TDM) can be used to optimize the antibiotic e...

Descripción completa

Detalles Bibliográficos
Autores principales: Köhler, Niklas, Karaköse, Hande, Grobbel, Hans-Peter, Hillemann, Doris, Andres, Sönke, König, Christina, Kalsdorf, Barbara, Brehm, Thomas Theo, Böttcher, Laura, Friesen, Inna, Hoffmann, Harald, Strelec, Dražen, Schaub, Dagmar, Peloquin, Charles A., Schmiedel, Stefan, Decosterd, Laurent A., Choong, Eva, Wicha, Sebastian G., Aarnoutse, Rob E., Lange, Christoph, Sánchez Carballo, Patricia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674734/
https://www.ncbi.nlm.nih.gov/pubmed/38004523
http://dx.doi.org/10.3390/pharmaceutics15112543