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A Single-Run HPLC–MS Multiplex Assay for Therapeutic Drug Monitoring of Relevant First- and Second-Line Antibiotics in the Treatment of Drug-Resistant Tuberculosis
The treatment of drug-resistant Mycobacterium tuberculosis relies on complex antibiotic therapy. Inadequate antibiotic exposure can lead to treatment failure, acquired drug resistance, and an increased risk of adverse events. Therapeutic drug monitoring (TDM) can be used to optimize the antibiotic e...
Autores principales: | Köhler, Niklas, Karaköse, Hande, Grobbel, Hans-Peter, Hillemann, Doris, Andres, Sönke, König, Christina, Kalsdorf, Barbara, Brehm, Thomas Theo, Böttcher, Laura, Friesen, Inna, Hoffmann, Harald, Strelec, Dražen, Schaub, Dagmar, Peloquin, Charles A., Schmiedel, Stefan, Decosterd, Laurent A., Choong, Eva, Wicha, Sebastian G., Aarnoutse, Rob E., Lange, Christoph, Sánchez Carballo, Patricia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674734/ https://www.ncbi.nlm.nih.gov/pubmed/38004523 http://dx.doi.org/10.3390/pharmaceutics15112543 |
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