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Pharmacokinetic–Pharmacodynamic Modeling of Midazolam in Pediatric Surgery

Midazolam (MDZ) is used for sedation in surgical procedures; its clinical effect is related to its receptor affinity and the dose administered. Therefore, a pharmacokinetic–pharmacodynamic (PK-PD) population model of MDZ in pediatric patients undergoing minor surgery is proposed. A descriptive, obse...

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Detalles Bibliográficos
Autores principales: Flores-Pérez, Carmen, Moreno-Rocha, Luis Alfonso, Chávez-Pacheco, Juan Luis, Noguez-Méndez, Norma Angélica, Flores-Pérez, Janett, Ortiz-Marmolejo, Delfina, Sarmiento-Argüello, Lina Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674765/
https://www.ncbi.nlm.nih.gov/pubmed/38004544
http://dx.doi.org/10.3390/pharmaceutics15112565