In Vitro and In Vivo Effects of Synthesis Novel Phenoxyacetamide Derivatives as Potent Apoptotic Inducer against HepG2 Cells through PARP-1 Inhibition

To discover potential cytotoxic agents, new semi-synthetic phenoxy acetamide derivatives, compound I and compound II, were synthesized, characterized, and screened for their cytotoxic activity against breast cancer (MCF-7) and liver cancer (HepG2) cell lines. The two compounds were more promising ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Sayed, Mai M., Nabil, Zohour I., El-Shenawy, Nahla S., Al-Eisa, Rasha A., Nafie, Mohamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674780/
https://www.ncbi.nlm.nih.gov/pubmed/38004390
http://dx.doi.org/10.3390/ph16111524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674780/
https://www.ncbi.nlm.nih.gov/pubmed/38004390
http://dx.doi.org/10.3390/ph16111524

Ejemplares similares