Cargando…
In Vitro and In Vivo Effects of Synthesis Novel Phenoxyacetamide Derivatives as Potent Apoptotic Inducer against HepG2 Cells through PARP-1 Inhibition
To discover potential cytotoxic agents, new semi-synthetic phenoxy acetamide derivatives, compound I and compound II, were synthesized, characterized, and screened for their cytotoxic activity against breast cancer (MCF-7) and liver cancer (HepG2) cell lines. The two compounds were more promising ag...
Autores principales: | Sayed, Mai M., Nabil, Zohour I., El-Shenawy, Nahla S., Al-Eisa, Rasha A., Nafie, Mohamed S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674780/ https://www.ncbi.nlm.nih.gov/pubmed/38004390 http://dx.doi.org/10.3390/ph16111524 |
Ejemplares similares
-
Encapsulation of Lovastatin in Zein Nanoparticles Exhibits Enhanced Apoptotic Activity in HepG2 Cells
por: Alhakamy, Nabil A., et al.
Publicado: (2019) -
Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation
por: Liu, Xiaoning, et al.
Publicado: (2018) -
Antiproliferative and apoptotic effects of β-elemene on human hepatoma HepG2 cells
por: Dai, Zhi-Jun, et al.
Publicado: (2013) -
Antiproliferative and Apoptotic Effects of Cardamonin against Hepatocellular Carcinoma HepG2 Cells
por: Badroon, Nassrin A., et al.
Publicado: (2020) -
Synthesis and Biological Evaluation of 2-Phenoxyacetamide Analogues, a Novel Class of Potent and Selective Monoamine Oxidase Inhibitors
por: Shen, Wei, et al.
Publicado: (2014)