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Development and Evaluation of Solid Dispersion-Based Sublingual Films of Nisoldipine

Nisoldipine (NIS) is a calcium channel blocker that exhibits poor bioavailability (~5%) due to low aqueous solubility and presystemic metabolism in the gut wall. In this context, the present work aimed to develop NIS solid dispersion (NISSD)-based sublingual films using solvent casting technique to...

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Detalles Bibliográficos
Autores principales: Alhamhoom, Yahya, Sharma, Abhay, Nanjappa, Shivakumar Hagalavadi, Kumar, Avichal, Alshishani, Anas, Ahmed, Mohammed Muqtader, Farhana, Syeda Ayesha, Rahamathulla, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674845/
https://www.ncbi.nlm.nih.gov/pubmed/38004454
http://dx.doi.org/10.3390/ph16111589