Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide

Peptide-based opioid ligands are important candidates for the development of novel, safer, and more effective analgesics to treat pain. To develop peptide-based safer analgesics, we synthesized a mixture-based cyclic pentapeptide library containing a total of 24,624 pentapeptides and screened the mi...

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Detalles Bibliográficos
Autores principales: Li, Yangmei, Eans, Shainnel O., Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A., McLaughlin, Jay P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674865/
https://www.ncbi.nlm.nih.gov/pubmed/38005269
http://dx.doi.org/10.3390/molecules28227548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674865/
https://www.ncbi.nlm.nih.gov/pubmed/38005269
http://dx.doi.org/10.3390/molecules28227548

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