Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma

An Ugi–Zhu three-component reaction (UZ-3CR) coupled in a one-pot manner to a cascade process (N-acylation/aza Diels–Alder cycloaddition/decarboxylation/dehydration) was performed to synthesize a series of pyrrolo[3,4-b]pyridin-5-ones in 20% to 92% overall yields using ytterbium triflate as a cataly...

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Detalles Bibliográficos
Autores principales: Morales-Salazar, Ivette, Garduño-Albino, Carlos E., Montes-Enríquez, Flora P., Nava-Tapia, Dania A., Navarro-Tito, Napoleón, Herrera-Zúñiga, Leonardo David, González-Zamora, Eduardo, Islas-Jácome, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674953/
https://www.ncbi.nlm.nih.gov/pubmed/38004428
http://dx.doi.org/10.3390/ph16111562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10674953/
https://www.ncbi.nlm.nih.gov/pubmed/38004428
http://dx.doi.org/10.3390/ph16111562

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