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Suitability of Polymyxin B as a Mucosal Adjuvant for Intranasal Influenza and COVID-19 Vaccines

Polymyxin B (PMB) is an antibiotic that exhibits mucosal adjuvanticity for ovalbumin (OVA), which enhances the immune response in the mucosal compartments of mice. Frequent breakthrough infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants indicate that the IgA antibody...

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Detalles Bibliográficos
Autores principales: Yoshino, Naoto, Yokoyama, Takuya, Sakai, Hironori, Sugiyama, Ikumi, Odagiri, Takashi, Kimura, Masahiro, Hojo, Wataru, Saino, Tomoyuki, Muraki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675063/
https://www.ncbi.nlm.nih.gov/pubmed/38006059
http://dx.doi.org/10.3390/vaccines11111727