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Identification of Crocetin as a Dual Agonist of GPR40 and GPR120 Responsible for the Antidiabetic Effect of Saffron

Crocin, a glycoside of crocetin, has been known as the principal component responsible for saffron’s antidiabetic, anticancer, and anti-inflammatory effects. Crocetin, originating from the hydrolytic cleavage of crocin in biological systems, was subjected to ligand-based virtual screening in this in...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaodi, Ahn, Dohee, Nam, Gibeom, Kwon, Jihee, Song, Songyi, Kang, Min Ji, Ahn, Hyejin, Chung, Sang J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675071/
https://www.ncbi.nlm.nih.gov/pubmed/38004168
http://dx.doi.org/10.3390/nu15224774