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Identification of Crocetin as a Dual Agonist of GPR40 and GPR120 Responsible for the Antidiabetic Effect of Saffron
Crocin, a glycoside of crocetin, has been known as the principal component responsible for saffron’s antidiabetic, anticancer, and anti-inflammatory effects. Crocetin, originating from the hydrolytic cleavage of crocin in biological systems, was subjected to ligand-based virtual screening in this in...
Autores principales: | Zhao, Xiaodi, Ahn, Dohee, Nam, Gibeom, Kwon, Jihee, Song, Songyi, Kang, Min Ji, Ahn, Hyejin, Chung, Sang J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675071/ https://www.ncbi.nlm.nih.gov/pubmed/38004168 http://dx.doi.org/10.3390/nu15224774 |
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