Esterase-Responsive Polyglycerol-Based Nanogels for Intracellular Drug Delivery in Rare Gastrointestinal Stromal Tumors

Rare gastrointestinal stromal tumors (GISTs) are caused by mutations in the KIT and PDGFRA genes. Avapritinib (BLU-285) is a targeted selective inhibitor for mutated KIT and PDGFRA receptors that can be used to treat these tumors. However, there are subtypes of GISTs that exhibit resistance against...

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Detalles Bibliográficos
Autores principales: Schötz, Sebastian, Griepe, Adele K., Goerisch, Björn B., Kortam, Sally, Vainer, Yael Shammai, Dimde, Mathias, Koeppe, Hanna, Wedepohl, Stefanie, Quaas, Elisa, Achazi, Katharina, Schroeder, Avi, Haag, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675119/
https://www.ncbi.nlm.nih.gov/pubmed/38004483
http://dx.doi.org/10.3390/ph16111618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675119/
https://www.ncbi.nlm.nih.gov/pubmed/38004483
http://dx.doi.org/10.3390/ph16111618

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