Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic Acid

Age-related macular degeneration (AMD) is the main cause of blindness in developed countries. AMD is characterized by the formation of drusen, which are lipidic deposits, between retinal pigment epithelium (RPE) and the choroid. One of the main molecules accumulated in drusen is 7-Ketocholesterol (7...

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Detalles Bibliográficos
Autores principales: Pariente, Ana, Peláez, Rafael, Ochoa, Rodrigo, Pérez-Sala, Álvaro, Villanueva-Martínez, Ángela, Bobadilla, Miriam, Larráyoz, Ignacio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675123/
https://www.ncbi.nlm.nih.gov/pubmed/38004569
http://dx.doi.org/10.3390/pharmaceutics15112590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675123/
https://www.ncbi.nlm.nih.gov/pubmed/38004569
http://dx.doi.org/10.3390/pharmaceutics15112590

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