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The Trends and Future Prospective of In Silico Models from the Viewpoint of ADME Evaluation in Drug Discovery

Drug discovery and development are aimed at identifying new chemical molecular entities (NCEs) with desirable pharmacokinetic profiles for high therapeutic efficacy. The plasma concentrations of NCEs are a biomarker of their efficacy and are governed by pharmacokinetic processes such as absorption,...

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Detalles Bibliográficos
Autores principales: Komura, Hiroshi, Watanabe, Reiko, Mizuguchi, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675155/
https://www.ncbi.nlm.nih.gov/pubmed/38004597
http://dx.doi.org/10.3390/pharmaceutics15112619