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The Trends and Future Prospective of In Silico Models from the Viewpoint of ADME Evaluation in Drug Discovery
Drug discovery and development are aimed at identifying new chemical molecular entities (NCEs) with desirable pharmacokinetic profiles for high therapeutic efficacy. The plasma concentrations of NCEs are a biomarker of their efficacy and are governed by pharmacokinetic processes such as absorption,...
Autores principales: | Komura, Hiroshi, Watanabe, Reiko, Mizuguchi, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675155/ https://www.ncbi.nlm.nih.gov/pubmed/38004597 http://dx.doi.org/10.3390/pharmaceutics15112619 |
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