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Harnessing Nanomedicine to Potentiate the Chemo-Immunotherapeutic Effects of Doxorubicin and Alendronate Co-Encapsulated in Pegylated Liposomes

Encapsulation of Doxorubicin (Dox), a potent cytotoxic agent and immunogenic cell death inducer, in pegylated (Stealth) liposomes, is well known to have major pharmacologic advantages over treatment with free Dox. Reformulation of alendronate (Ald), a potent amino-bisphosphonate, by encapsulation in...

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Detalles Bibliográficos
Autores principales: Gabizon, Alberto, Shmeeda, Hilary, Draper, Benjamin, Parente-Pereira, Ana, Maher, John, Carrascal-Miniño, Amaia, de Rosales, Rafael T. M., La-Beck, Ninh M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675201/
https://www.ncbi.nlm.nih.gov/pubmed/38004584
http://dx.doi.org/10.3390/pharmaceutics15112606