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Harnessing Nanomedicine to Potentiate the Chemo-Immunotherapeutic Effects of Doxorubicin and Alendronate Co-Encapsulated in Pegylated Liposomes
Encapsulation of Doxorubicin (Dox), a potent cytotoxic agent and immunogenic cell death inducer, in pegylated (Stealth) liposomes, is well known to have major pharmacologic advantages over treatment with free Dox. Reformulation of alendronate (Ald), a potent amino-bisphosphonate, by encapsulation in...
Autores principales: | Gabizon, Alberto, Shmeeda, Hilary, Draper, Benjamin, Parente-Pereira, Ana, Maher, John, Carrascal-Miniño, Amaia, de Rosales, Rafael T. M., La-Beck, Ninh M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675201/ https://www.ncbi.nlm.nih.gov/pubmed/38004584 http://dx.doi.org/10.3390/pharmaceutics15112606 |
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