Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity

Benzimidazole anthelmintic drugs hold promise for repurposing as cancer treatments due to their interference with tubulin polymerization and depolymerization, manifesting anticancer properties. We explored the potential of benzimidazole compounds with a piperazine fragment at C-2 as tubulin-targetin...

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Detalles Bibliográficos
Autores principales: Anichina, Kameliya, Mavrova, Anelia, Vuchev, Dimitar, Popova-Daskalova, Galya, Bassi, Giada, Rossi, Arianna, Montesi, Monica, Panseri, Silvia, Fratev, Filip, Naydenova, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675210/
https://www.ncbi.nlm.nih.gov/pubmed/38004384
http://dx.doi.org/10.3390/ph16111518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675210/
https://www.ncbi.nlm.nih.gov/pubmed/38004384
http://dx.doi.org/10.3390/ph16111518

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