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Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity
Benzimidazole anthelmintic drugs hold promise for repurposing as cancer treatments due to their interference with tubulin polymerization and depolymerization, manifesting anticancer properties. We explored the potential of benzimidazole compounds with a piperazine fragment at C-2 as tubulin-targetin...
Autores principales: | Anichina, Kameliya, Mavrova, Anelia, Vuchev, Dimitar, Popova-Daskalova, Galya, Bassi, Giada, Rossi, Arianna, Montesi, Monica, Panseri, Silvia, Fratev, Filip, Naydenova, Emilia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675210/ https://www.ncbi.nlm.nih.gov/pubmed/38004384 http://dx.doi.org/10.3390/ph16111518 |
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