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Rational Design of AAV-rh74, AAV3B, and AAV8 with Limited Liver Targeting

Recombinant adeno-associated viruses (rAAVs) have become one of the leading gene therapies for treating a variety of diseases. One factor contributing to rAAVs’ success is the fact that a wide variety of tissue types can be transduced by different serotypes. However, one commonality amongst most ser...

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Detalles Bibliográficos
Autores principales: Chan, Christopher, Harris, Kathryn K., Zolotukhin, Sergei, Keeler, Geoffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675213/
https://www.ncbi.nlm.nih.gov/pubmed/38005848
http://dx.doi.org/10.3390/v15112168