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Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films

Rosuvastatin (RSV) is a widely used cholesterol-lowering medication, but its limited bioavailability due to its susceptibility to stomach pH and extensive first-pass metabolism poses a significant challenge. A fast-dissolving film (FDF) formulation of RSV was developed, characterized, and compared t...

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Detalles Bibliográficos
Autores principales: Ashraf, Ibrahim, Hanna, Pierre A., Gad, Shadeed, Abd-Allah, Fathy I., El-Say, Khalid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675329/
https://www.ncbi.nlm.nih.gov/pubmed/38004618
http://dx.doi.org/10.3390/pharmaceutics15112640