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Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films
Rosuvastatin (RSV) is a widely used cholesterol-lowering medication, but its limited bioavailability due to its susceptibility to stomach pH and extensive first-pass metabolism poses a significant challenge. A fast-dissolving film (FDF) formulation of RSV was developed, characterized, and compared t...
Autores principales: | Ashraf, Ibrahim, Hanna, Pierre A., Gad, Shadeed, Abd-Allah, Fathy I., El-Say, Khalid M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675329/ https://www.ncbi.nlm.nih.gov/pubmed/38004618 http://dx.doi.org/10.3390/pharmaceutics15112640 |
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