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Impact of Pharmacogenomics in Clinical Practice

Polymorphisms of genes encoding drug metabolizing enzymes and transporters can significantly modify pharmacokinetics, and this can be associated with significant differences in drug efficacy, safety, and tolerability. Moreover, genetic variants of some components of the immune system can explain cli...

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Detalles Bibliográficos
Autores principales: Principi, Nicola, Petropulacos, Kyriakoula, Esposito, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675377/
https://www.ncbi.nlm.nih.gov/pubmed/38004461
http://dx.doi.org/10.3390/ph16111596