Cargando…

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population—Current Advances, Challenges, and Opportunities

Physiologically based pharmacokinetic (PBPK) modeling is an approach to predicting drug pharmacokinetics, using knowledge of the human physiology involved and drug physiochemical properties. This approach is useful when predicting drug pharmacokinetics in under-studied populations, such as pediatric...

Descripción completa

Detalles Bibliográficos
Autores principales: Dinh, Jean, Johnson, Trevor N., Grimstein, Manuela, Lewis, Tamorah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675397/
https://www.ncbi.nlm.nih.gov/pubmed/38004559
http://dx.doi.org/10.3390/pharmaceutics15112579