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Physiologically Based Pharmacokinetics Modeling in the Neonatal Population—Current Advances, Challenges, and Opportunities
Physiologically based pharmacokinetic (PBPK) modeling is an approach to predicting drug pharmacokinetics, using knowledge of the human physiology involved and drug physiochemical properties. This approach is useful when predicting drug pharmacokinetics in under-studied populations, such as pediatric...
Autores principales: | Dinh, Jean, Johnson, Trevor N., Grimstein, Manuela, Lewis, Tamorah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675397/ https://www.ncbi.nlm.nih.gov/pubmed/38004559 http://dx.doi.org/10.3390/pharmaceutics15112579 |
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