Glibenclamide-Loaded Nanoparticles Reduce NLRP3 Inflammasome Activation and Modulate miR-223-3p/miR-7-1-5p Expression in THP-1 Cells

The anti-hyperglycemic drug glibenclamide (Glb) might represent an interesting therapeutic option in human neurodegenerative diseases because of its anti-inflammatory activity and its ability to downregulate activation of the NLRP3 inflammasome. Bi-functionalized liposomes that can cross the blood–b...

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Detalles Bibliográficos
Autores principales: Mancuso, Roberta, Citterio, Lorenzo Agostino, Agostini, Simone, Marventano, Ivana, La Rosa, Francesca, Re, Francesca, Seneci, Pierfausto, Saresella, Marina, Clerici, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675475/
https://www.ncbi.nlm.nih.gov/pubmed/38004455
http://dx.doi.org/10.3390/ph16111590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675475/
https://www.ncbi.nlm.nih.gov/pubmed/38004455
http://dx.doi.org/10.3390/ph16111590

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