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Quantitative Analysis of a Pilot Transwell Barrier Model with Automated Sampling and Mathematical Modeling
In the preclinical phase of drug development, it is necessary to determine how the active compound can pass through the biological barriers surrounding the target tissue. In vitro barrier models provide a reliable, low-cost, high-throughput solution for screening substances early in the drug candida...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675510/ https://www.ncbi.nlm.nih.gov/pubmed/38004624 http://dx.doi.org/10.3390/pharmaceutics15112646 |