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Quantitative Analysis of a Pilot Transwell Barrier Model with Automated Sampling and Mathematical Modeling

In the preclinical phase of drug development, it is necessary to determine how the active compound can pass through the biological barriers surrounding the target tissue. In vitro barrier models provide a reliable, low-cost, high-throughput solution for screening substances early in the drug candida...

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Detalles Bibliográficos
Autores principales: Tárnoki-Zách, Júlia, Bősze, Szilvia, Czirók, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675510/
https://www.ncbi.nlm.nih.gov/pubmed/38004624
http://dx.doi.org/10.3390/pharmaceutics15112646