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Targeting Glucose Metabolism in Cancer Cells as an Approach to Overcoming Drug Resistance

The “Warburg effect” consists of a metabolic shift in energy production from oxidative phosphorylation to glycolysis. The continuous activation of glycolysis in cancer cells causes rapid energy production and an increase in lactate, leading to the acidification of the tumour microenvironment, chemo-...

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Detalles Bibliográficos
Autores principales: Cunha, Andrea, Silva, Patrícia M. A., Sarmento, Bruno, Queirós, Odília
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675572/
https://www.ncbi.nlm.nih.gov/pubmed/38004589
http://dx.doi.org/10.3390/pharmaceutics15112610