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Comparative Analysis of the Physicochemical and Biological Characteristics of Freeze-Dried PEGylated Cationic Solid Lipid Nanoparticles

Cationic solid-lipid nanoparticles (cSLNs) have become a promising tool for gene and RNA therapies. PEGylation (PEG) is crucial in enhancing particle stability and protection. We evaluated the impact of PEG on the physicochemical and biological characteristics of cholesteryl-oleate cSLNs (CO-cSLNs)....

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Detalles Bibliográficos
Autores principales: Narváez-Narváez, David A., Duarte-Ruiz, María, Jiménez-Lozano, Sandra, Moreno-Castro, Cristina, Vargas, Ronny, Nardi-Ricart, Anna, García-Montoya, Encarna, Pérez-Lozano, Pilar, Suñé-Negre, Josep Mª, Hernández-Munain, Cristina, Suñé, Carlos, Suñé-Pou, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675625/
https://www.ncbi.nlm.nih.gov/pubmed/38004448
http://dx.doi.org/10.3390/ph16111583