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Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of pediatric morbidity and mortality. Young children are at high risk of TB following Mtb exposure, and this vulnerability is secondary to insufficient host immunity during early life. Our primary objective was to...

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Detalles Bibliográficos
Autores principales: Morrow, Erin, Liu, Qijia, Kiguli, Sarah, Swarbrick, Gwendolyn, Nsereko, Mary, Null, Megan D., Cansler, Meghan, Mayanja-Kizza, Harriet, Boom, W. Henry, Chheng, Phalkun, Nyendak, Melissa R., Lewinsohn, David M., Lewinsohn, Deborah A., Lancioni, Christina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675744/
https://www.ncbi.nlm.nih.gov/pubmed/38003817
http://dx.doi.org/10.3390/pathogens12111353