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The Metabolic Fingerprint of Doxorubicin-Induced Cardiotoxicity in Male CD-1 Mice Fades Away with Time While Autophagy Increases

The cardiotoxicity of doxorubicin (DOX) may manifest at the beginning/during treatment or years after, compromising patients’ quality of life. We intended to study the cardiac pathways one week (short-term, control 1 [CTRL1] and DOX1 groups) or five months (long-term, CTRL2 and DOX2 groups) after DO...

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Detalles Bibliográficos
Autores principales: Brandão, Sofia Reis, Reis-Mendes, Ana, Neuparth, Maria João, Carvalho, Félix, Ferreira, Rita, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675798/
https://www.ncbi.nlm.nih.gov/pubmed/38004479
http://dx.doi.org/10.3390/ph16111613